REGENZYME: Mastering Regioselectivity in Enzymatic Synthesis

In enzymatic synthesis of carbohydrates, regioselectivity is the key to obtaining products of the desired structure. Defined carbohydrates are crucial in cell communication, therapeutics, beneficial foods, and future biomaterials. This project will investigate the regioselectivity of a wide range of enzymes and combine several methods to understand the enzyme-carbohydrate interactions that determine regioselectivity at molecular level. The grant funds one Ph.D. student and two postdocs.