Creating multiple microenvironments within the same reactor setup for sequential enzymatic reactions at industrial level

Recipient
Manuel Pinelo
Technical University of Denmark
Project number:
00028005
Grant amount
1.251.451 DKK
Year
2019

Project description

Sequential reactions occurring in living cells where several enzymes are involved occur at different conditions of temperature and pH sometimes. Cells have developed sophisticated “architectural” structures so enzymes activated at different conditions can cohabit and participate in the same sequential reactions. The purpose of this project is to study such mechanisms and try to select the optimal chemicals to mimic such structures in artificial reactors. This would potentially allow to conduct sequential reactions at industrial scale, in which all the enzymes involved will act at high efficiencies.