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From transparent fruit flies to the meaning of baby cries

Once again this year, bold and innovative ideas have received support through the Villum Foundation’s programme for unconventional research projects: Villum Experiment
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The Villum Foundation has awarded funding to 52 research projects, all united by their courage to think differently and take risks. The projects were selected through an anonymous peer-review process, where the originality and potential of the idea outweigh the researcher’s CV. This creates space for the unexpected and the untested – which is precisely the essence of Villum Experiment.

“Villum Experiment is about giving room to ideas that don’t necessarily fit into conventional frameworks. We believe that major breakthroughs often hide in the quirky and the wild,” says Thomas Bjørnholm, Director of Research at the Villum Foundation, and continues:

“By removing names and credentials from the evaluation, we open up the field to curiosity and courage.”

Why do ticks bite some people more than others?

One of this year’s grant recipients, Professor Karen Angeliki Krogfelt from Roskilde University, will investigate why some people are more attractive to ticks than others. The project aims to identify which skin bacteria are particularly enticing to this small but potentially dangerous parasite.

“By observing ticks’ preferences for skin bacteria, we hope to better understand why they choose to bite certain animals and humans over others. Our research could lead to new methods for reducing the risk of tick bites – for example, by applying specific skin bacteria that act as repellents,” says Karen Angeliki Krogfelt.

Enzymes and AI in the fight against microplastics

Another grant recipient, postdoc Colleen Varaidzo Manyumwa from DTU, will develop a new method to break down microplastics. Microplastics are notoriously difficult to remove from our food, water, and air – making them one of the world’s major environmental culprits. Colleen’s project will explore how enzymes, aided by artificial intelligence, can recognise and degrade microplastics, even when composed of many different plastic types.

Fruit flies can reveal the building blocks of life

Postdoc Jiawei Xu from Aarhus University will use genetic engineering to create a transparent fruit fly. The project could offer new insights into how tissues develop and organs form, by making it possible to observe biological processes that have so far been hidden behind the insect’s exoskeleton.

From baby cries to ancient vertebrates

Among the other projects is an experiment to map what infants are actually trying to communicate when they cry. Participating parents will receive feedback on their babies’ crying patterns in exchange for data from their baby monitors. Another project investigates why some vertebrates live up to 200 years, and a third aims to accelerate species identification using machine learning.

“It’s precisely this kind of research – the kind that dares to ask unexpected and profound questions – that we want to promote through Villum Experiment,” says Thomas Bjørnholm.

“We don’t know what will create new paradigms – what will give us a better understanding of the world and lead to groundbreaking insights. That’s why we must dare to support the unpredictable.”

Villum Foundation launched Villum Experiment in 2017. Since then, the foundation has awarded nearly DKK 900 million to bold and unconventional research ideas through the program.

About the Villum Experiment Programme

• Focus on innovative and unconventional research ideas
• Anonymous evaluation ensures emphasis on the potential of the idea rather than the researcher's merits
• High risk factor and potential for breakthroughs
• Supports research ideas in their early stages
• Annually awards approximately 50 grants

Villum Experiment recipients 2025: