Ancient RNA: uncovering the missing link to reveal a new era in Paleogenetics.
Modtager
Emilio Mármol Sánchez
Københavns Universitet
Projektnummer:
00057875
Bevilliget
1.999.548 DKK
År
2023
Projektbeskrivelse
- I propose there are plausible yet currently overlooked grounds supporting the extensive survival of RNA in natural history collections.
- I will explore this by applying recently developed methods for extracting and characterizing highly fragmented nucleic acids, thus facilitating the dawn of paleotranscriptomics.
- If RNA survival is as prevalent as I anticipate, the findings stand to initiate a new era in paleogenetics, with a holistic approach to the central dogma of molecular biology (from DNA to RNA and proteins). This has the potential to both transform our understanding of animal and associated pathogens evolution and contribute towards future de-extinction efforts.
